Current Research

Low Dose Naltrexone (LDN) Trial

Low Dose Naltrexone (LDN) Trial

Naltrexone is a medication that has been used in the treatment of excessive alcohol and opioids and for some types of itchiness. It has also been used, in low doses, for the relief of symptoms related to fibromyalgia (FM) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Overall, studies have found that LDN is safe and well-tolerated. […]

ME/CFS MRI Study

ME/CFS MRI Study

There is absence of diagnostic biomarkers and treatments for ME/CFS despite its high prevalence and disabling nature. Using multimodal MRI, the aim of the study is to investigate for changes in brain function, metabolism and anatomy that might underlie inflammation in patients with ME/CFS. This pilot study will enable the development of a larger scale […]

CCDP Data Registry

CCDP Data Registry

Established in 2017, and in collaboration with the BC Women’s Complex Chronic Diseases Program patients are invited to participate in the CCDP Data Registry. The data registry collects prospective data to add to the sparse available clinical and spectrum of care information characterizing the patient population which will lead to a better understanding of these […]

The Contribution of Viral Infections to ME

The Contribution of Viral Infections to ME

Viral infections have been frequently associated with ME/CFS, though their causal role has been unclear, with their role attributed as a triggering factor rather than due to a persistent or chronic infection. This study will look at the contributing role of exposure to specific viral pathogens to the development of ME through accessing the existing […]

CCDP Questionnaire Validation Study

CCDP Questionnaire Validation Study

This study will evaluate whether three patient-reported questionnaires on mental health and phenotype categories (patient subgroups) are suitable for use in the Complex Chronic Disease Program (CCDP) clinical population. This will involve recruiting CCDP patients to complete questionnaires at two time points and then analyzing and comparing the proposed mental health and phenotyping questionnaire scores […]