Publications

2024

Kaur, R.; Greeley, B.; Ciok, A.; Mehta, K.; Tsai, M.; Robertson, H.; Debelic, K.; Zhang, L.X.; Nelson, T.; Boulter, T.; et al. A Multimodal Magnetic Resonance Imaging Study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Feasibility and Clinical Correlation. Medicina 2024, 60, 1370. https://doi.org/10.3390/medicina60081370

Naik, H., Cooke, E., Boulter, T., Dyer, R., Bone, J. N., Tsai, M., Cristobal, J., McKay, R. J., Song, X., & Nacul, L. (2024). Low-dose naltrexone for post-COVID fatigue syndrome: a study protocol for a double-blind, randomised trial in British Columbia. BMJ open14(5), e085272. https://doi.org/10.1136/bmjopen-2024-085272

2023

Steiner, S., Fehrer, A., Hoheisel, F., Schoening, S., Aschenbrenner, A., Babel, N., Bellmann-Strobl, J., Finke, C., Fluge, Ø., Froehlich, L., Goebel, A., Grande, B., Haas, J. P., Hohberger, B., Jason, L. A., Komaroff, A. L., Lacerda, E., Liebl, M., Maier, A., Mella, O., Nacul, L., … Scheibenbogen, C. (2023). Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center. Autoimmunity reviews22(11), 103452. https://doi.org/10.1016/j.autrev.2023.103452

Domingues, T. D., Malato, J., Grabowska, A. D., Lee, J. S., Ameijeiras-Alonso, J., Biecek, P., Graça, L., Mouriño, H., Scheibenbogen, C., Westermeier, F., Nacul, L., et al. (2023). Association analysis between symptomology and herpesvirus IgG antibody concentrations in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis. Heliyon9(7), e18250. https://doi.org/10.1016/j.heliyon.2023.e18250

Grabowska, A. D., Westermeier, F., Nacul, L., Lacerda, E., & Sepúlveda, N. (2023). The importance of estimating prevalence of ME/CFS in future epidemiological studies of long COVID. Frontiers in public health11, 1275827. https://doi.org/10.3389/fpubh.2023.1275827

Magel, T., Meagher, E., Boulter, T., Albert, A., Tsai, M., Muñoz, C., Carlsten, C., Johnston, J., Wong, A. W., Shah, A., Ryerson, C., Mckay, R. J., & Nacul, L. (2023). Fatigue presentation, severity, and related outcomes in a prospective cohort following post-COVID-19 hospitalization in British Columbia, Canada. Frontiers in medicine10, 1179783. https://doi.org/10.3389/fmed.2023.1179783

2022

Kingdon, C.C., Lowe, A., Shepherd, C., & Nacul, L. (2022). What Primary Care Practitioners Need to Know about the New NICE Guideline for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in Adults. Healthcare, 10(12), 2438; https://doi.org/10.3390/healthcare10122438

Oliveira, A. M. D. S. S., Carvalho, M. A., Nacul, L., et al. (2022). Post-Viral Fatigue Following SARS-CoV-2 Infection during Pregnancy: A Longitudinal Comparative Study. International journal of environmental research and public health, 19(23), 15735. https://doi.org/10.3390/ijerph192315735 

Tami, A., van der Gun, B. T. F., Wold, K. I., Vincenti-González, M. F., Veloo, A. C. M., Knoester, M., Harmsma, V. P. R., de Boer, G. C., Huckriede, A. L. W., Pantano, D., Gard, L., Rodenhuis-Zybert, I. A., Upasani, V., Smit, J., Dijkstra, A. E., de Haan, J. J., van Elst, J. M., van den Boogaard, J., O’ Boyle, S., Nacul, L., … Friedrich, A. W. (2022). The COVID HOME study research protocol: Prospective cohort study of non-hospitalised COVID-19 patients. PloS one17(11), e0273599. https://doi.org/10.1371/journal.pone.0273599

Naik, H., Shao, S., Tran, K. C., Wong, A. W., Russell, J. A., Khor, E., Nacul, L., McKay, R. J., Carlsten, C., Ryerson, C. J., & Levin, A. (2022). Evaluating fatigue in patients recovering from COVID-19: validation of the fatigue severity scale and single item screening questions. Health and quality of life outcomes, 20(1), 170. https://doi.org/10.1186/s12955-022-02082-x

O’Boyle, S., Nacul, L., Nacul, F. E., Mudie, K., Kingdon, C. C., Cliff, J. M., Clark, T. G., Dockrell, H. M., & Lacerda, E. M. (2022). A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in medicine, 8, 688159. https://doi.org/10.3389/fmed.2021.688159

Brellier, F., Pujades-Rodriguez, M., Powell, E., Mudie, K., Mattos Lacerda, E., Nacul, L., & Wing, K. (2022). Incidence of Lyme disease in the United Kingdom and association with fatigue: A population-based, historical cohort study. PLOS ONE, 17(3). https://doi.org/10.1371/journal.pone.0265765

Aoun Sebaiti, M., Hainselin, M., Gounden, Y., Sirbu, C. A., Sekulic, S., Lorusso, L., Nacul, L., & Authier, F. J. (2022). Systematic review and meta-analysis of cognitive impairment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Scientific reports, 12(1), 2157. https://doi.org/10.1038/s41598-021-04764-w

2021

O’Boyle, S., Nacul, L., Nacul, F. E., Mudie, K., Kingdon, C. C., Cliff, J. M., Clark, T. G., Dockrell, H. M., & Lacerda, E. M. (2022). A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in medicine8, 688159. https://doi.org/10.3389/fmed.2021.688159

Nelson, T., Zhang, L. X., Guo, H., Nacul, L., & Song, X. (2021). Brainstem Abnormalities in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Scoping Review and Evaluation of Magnetic Resonance Imaging Findings. Frontiers in neurology12, 769511. https://doi.org/10.3389/fneur.2021.769511

Lee, J. S., Lacerda, E. M., Nacul, L., Kingdon, C. C., Norris, J., O’Boyle, S., Roberts, C. H., Palla, L., Riley, E. M., & Cliff, J. M. (2021). Salivary DNA Loads for Human Herpesviruses 6 and 7 Are Correlated With Disease Phenotype in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in medicine8, 656692. https://doi.org/10.3389/fmed.2021.656692

Malato, J., Sotzny, F., Bauer, S., Freitag, H., Fonseca, A., Grabowska, A. D., Graça, L., Cordeiro, C., Nacul, L., Lacerda, E. M., Castro-Marrero, J., Scheibenbogen, C., Westermeier, F., & Sepúlveda, N. (2021). The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encephalomyelitis/chronic fatigue syndrome: A meta-analysis of public DNA methylation and gene expression data. Heliyon7(8), e07665. https://doi.org/10.1016/j.heliyon.2021.e07665

Domingues, T. D., Grabowska, A. D., Lee, J. S., Ameijeiras-Alonso, J., Westermeier, F., Scheibenbogen, C., Cliff, J. M., Nacul, L., Lacerda, E. M., Mouriño, H., & Sepúlveda, N. (2021). Herpesviruses Serology Distinguishes Different Subgroups of Patients From the United Kingdom Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Biobank. Frontiers in medicine8, 686736. https://doi.org/10.3389/fmed.2021.686736

Nacul, L., Authier, F. J., Scheibenbogen, C., Lorusso, L., Helland, I. B., Martin, J. A., Sirbu, C. A., Mengshoel, A. M., Polo, O., Behrends, U., Nielsen, H., Grabowski, P., Sekulic, S., Sepulveda, N., Estévez-López, F., Zalewski, P., Pheby, D. F. H., Castro-Marrero, J., Sakkas, G. K., Capelli, E., … Lacerda, E. M. (2021). European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): Expert Consensus on the Diagnosis, Service Provision, and Care of People with ME/CFS in Europe. Medicina (Kaunas, Lithuania)57(5), 510. https://doi.org/10.3390/medicina57050510

Malato, J., Sotzny, F., Bauer, S., Freitag, H., Fonseca, A., Grabowska, A. D., Graça, L., Cordeiro, C., Nacul, L., Lacerda, E. M., Castro-Marrero, J., Scheibenbogen, C., Westermeier, F., & Sepúlveda, N. (2021). The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: analysis of high-throughput epigenetic and gene expression studies. medRxiv : the preprint server for health sciences, 2021.03.23.21254175. https://doi.org/10.1101/2021.03.23.21254175

2020

Nacul, L., O’Boyle, S., Palla, L., Nacul, F. E., Mudie, K., Kingdon, C. C., Cliff, J. M., Clark, T. G., Dockrell, H. M., & Lacerda, E. M. (2020). How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS. Frontiers in neurology11, 826. https://doi.org/10.3389/fneur.2020.00826

Friedberg, F., Sunnquist, M., & Nacul, L. (2020). Rethinking the Standard of Care for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Journal of general internal medicine35(3), 906–909. https://doi.org/10.1007/s11606-019-05375-y

Estévez-López, F., Mudie, K., Wang-Steverding, X., Bakken, I. J., Ivanovs, A., Castro-Marrero, J., Nacul, L., Alegre, J., Zalewski, P., Słomko, J., Strand, E. B., Pheby, D., Shikova, E., Lorusso, L., Capelli, E., Sekulic, S., Scheibenbogen, C., Sepúlveda, N., Murovska, M., & Lacerda, E. (2020). Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology. Journal of clinical medicine9(5), 1557. https://doi.org/10.3390/jcm9051557

Grabowska, A. D., Lacerda, E. M., Nacul, L., & Sepúlveda, N. (2020). Review of the Quality Control Checks Performed by Current Genome-Wide and Targeted-Genome Association Studies on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Frontiers in pediatrics8, 293. https://doi.org/10.3389/fped.2020.00293

Kingdon, C., Giotas, D., Nacul, L., & Lacerda, E. (2020). Health Care Responsibility and Compassion-Visiting the Housebound Patient Severely Affected by ME/CFS. Healthcare (Basel, Switzerland)8(3), 197. https://doi.org/10.3390/healthcare8030197